Minneapolis ( ()) is the most populous city in the U.S. state of Minnesota and the seat of Hennepin County. With a population of 429,954 as of 2020, it is the 46th most populous city in the US. Seven counties encompassing Minneapolis and its neighbor Saint Paul are known as the Twin Cities. In 2019, those counties are among sixteen making up the Minneapolis–St. Paul–Bloomington MN–WI metropolitan area of 3.6 million, and twenty-two making up the combined statistical area of 4.0 million — the sixteenth largest metropolitan area in the United States.